Longevity
Longevity news and research from Life and Health Today, updated daily.
- Sesame compound eased alcohol-related gut aging in middle-aged mice
A sesame-derived compound called sesaminol reduced signs of intestinal aging and inflammation in middle-aged mice given alcohol daily for ten weeks, according to a study published in GeroScience....
- Male tree shrews outlived females by median lifespan in first detailed captive colony study
Researchers at the University of Alabama at Birmingham tracked their Northern tree shrew colony and found males had a longer median lifespan than females, though maximum lifespan and mortality...
- FDA proposes updating nutrient rules for infant formula in phased review
The Food and Drug Administration published a proposed rule on October 29, 2026, that would adjust required levels for four of the roughly 30 nutrients infant formula must contain, update labeling...
- Palladium membranes destroy PFAS in water, not just filter them out
A team at Arizona State University and four partner institutions has built membranes that capture six regulated 'forever chemicals' and chemically break them apart, rather than concentrating them...
- Scientists find the protein that slows egg aging in mice
A protein called OMC1 helps hold chromosomes together inside eggs across a female's reproductive life, researchers report in Nature Aging. When the gene for OMC1 was removed from mice, chromosome...
- Strength declines faster than most people expect. Resistance training is the clearest answer.
Muscle strength peaks in your 30s and early 40s, then falls roughly 1 to 2 percent a year, with the drop accelerating after 70. A detailed guide from physician and longevity researcher Peter Attia...
- Pennsylvania measles outbreak tops 1,300 cases, straining clinics and dividing parents
A pediatrician at the Children's Hospital of Philadelphia describes treating families on opposite sides of the vaccine debate during an active measles outbreak. The piece lays out what the disease...
- Three family doctors on what actually moves the needle in obesity care
A Medscape report asked three primary care physicians how they set goals with patients managing obesity, and their answers center on self-monitoring, accountability partners, and knowing a...
- A scan-based organ-age model found nine proteins tied to mortality across four organs
Researchers used MRI scans and body measurements from nearly 47,000 people to estimate how fast the brain, heart, liver and pancreas are each aging, independently of one another. The study,...
- Exercise linked to slower biological aging clock readings in older adults with poor sleep
A study published in GeroScience tracked 890 adults aged 20 to 102 and found that higher physical activity was associated with slower readings on several biological aging clocks, particularly in...
- Four medical societies map women's heart health across a lifetime
A new framework published in the journal Circulation divides women's cardiovascular health into four life stages, from adolescence through postmenopause, and argues that hormonal transitions long...
- Biotech IPOs jumped 573% in 2026, but early-stage startups are still struggling
Biotech's public markets had their strongest year since the post-COVID slump, with IPO proceeds jumping more than fivefold compared to 2025, according to investment bank Locust Walk. The recovery...
- Tovecimig plus paclitaxel lifted response rates in biliary tract cancer, but survival gain did not follow
A phase II/III trial found that adding the experimental bispecific antibody tovecimig to standard chemotherapy more than tripled the response rate in patients with previously treated advanced...
- Last Year's $1,000 of Medical Care Costs $1,015 Now
Life and Health Today's monthly cost reading for September: medical care prices moved +1.5% over the year, slower than overall inflation at +3.7%.
- Senators push for stricter rules on Medicaid computer systems as new work requirements loom
Three Democratic senators are calling on federal regulators to impose mandatory performance standards on the private contractors that run Medicaid eligibility systems for most states. The push...
- CAR T-cell therapy is curing some blood cancers. Here is where oncology stands now.
Fifteen years after The Emperor of All Maladies, oncologist Siddhartha Mukherjee sat down with physician Peter Attia to map what has genuinely changed in cancer science. Some of it is remarkable....
- Healthy habits explain only a slice of the longevity gap between rich and poor
A 20-year study of 33,541 older adults aged 65 and over across 23 provinces in China found that people with lower socioeconomic status faced a 25% higher risk of early death and a 46% higher risk...
- Wegovy's weight-loss pill reached 100,000 new prescriptions a month in two months
The daily semaglutide tablet was taken up faster in its first months than the injections were, and injection prescriptions did not decline, according to a study in Annals of Internal Medicine....
- Fat in aging muscle may signal decline, but the science is still early
A review of population studies finds that fat seeping into muscle tissue accumulates steadily with age, independent of body weight or activity level, and tracks with losses in strength and...
- Lack of community toilets linked to higher depression risk in older Indians
A large national study in India found that older adults living in communities with the fewest toilets were 38% more likely to show signs of depression than those in communities with the most. The...
- FDA approves once-monthly olanzapine injection that skips sedation monitoring
The US Food and Drug Administration has cleared a new subcutaneous, once-monthly injectable form of olanzapine, a long-established antipsychotic, for adults with schizophrenia. Unlike the only...
- Genetic risk scores for hearing loss sharpen when built on real test data, not billing codes
A team at Vanderbilt University Medical Center found that using actual audiometric measurements, rather than the diagnostic billing codes that most genetic studies rely on, produced far more...
- Vitamin D2 supplements found to lower the body's own D3 levels
A meta-analysis of randomised trials found that taking vitamin D2, the plant-derived form common in supplements, reduces circulating vitamin D3, the form the body makes from sunlight. Researchers...
- Falling cardiolipin levels drive age-related muscle changes in mice
A lipid that shapes the inner membrane of mitochondria declines with age, and researchers have now shown in mice that this decline alone is enough to trigger the muscle-fiber shifts seen in...
- Cancer treatment can damage the heart silently, decades after it ends
Certain chemotherapy drugs and chest radiation can injure heart muscle in ways that produce no symptoms for ten or twenty years. A Spanish nuclear medicine specialist says primary care doctors are...
- Semaglutide reduced heart and liver damage in animals without weight loss
A study published in the European Heart Journal found that semaglutide improved heart function and reversed liver scarring in two animal models of a common form of heart failure, even when the...
- Aging biomarker scientists gather at Harvard to set standards the field still lacks
The Biomarkers of Aging Consortium is bringing together researchers, regulators, and funders in Boston this October to agree on how biological age should be measured and what those measurements...
- Early aggressive Crohn's treatment cuts surgery risk at five years, trial finds
A five-year follow-up of a UK randomised trial found that starting newly diagnosed Crohn's patients on powerful immune-suppressing drugs immediately, rather than working up to them gradually,...
- Salk researchers map 1,000-plus unknown microproteins in Alzheimer's brain tissue
A new atlas built from nearly 500 postmortem human brain samples has identified more than 1,000 tiny proteins that standard databases had missed entirely. One of them appears to be downregulated...
- Blood proteins and epigenetic clocks both predict death risk, but brain measures edge ahead
A study of 861 older Scottish adults tracked over 16 years found that established biological markers, including an epigenetic clock, brain volume and lung function, predicted all-cause mortality...
- New sleep drugs not linked to falls or fractures in insomnia patients
A meta-analysis published in the Journal of the American Geriatrics Society found no clear association between a newer class of sleep drugs and increased odds of falls or fractures in adults with...
- Semaglutide linked to fewer inflammatory blood cells in small T2D study
A study of 16 adults with type 2 diabetes found that six months on semaglutide was associated with a measurable drop in a type of inflammatory immune cell circulating in the blood. The finding,...
- Blood proteins may flag Alzheimer's risk earlier than spinal fluid, monkey study finds
Researchers profiling proteins in the blood and spinal fluid of 66 rhesus macaques found that plasma markers of amyloid buildup tracked brain pathology more closely than the same markers measured...
- Liver growth hormone signalling shapes ageing pace in mice, study finds
Mice engineered to lack growth hormone receptors only in their liver aged faster, lived shorter lives and developed worse metabolic disease than normal mice, according to a study published in...
- A blood score built on AI may track how many 'zombie cells' you carry
Researchers have developed a deep-learning tool that converts dozens of blood proteins into a single score for cellular senescence, the accumulation of damaged cells that refuse to die. In a large...
- Kidney protection from GLP-1 and SGLT-2 drugs depends on one blood marker
A large observational study published in The BMJ found that two widely used diabetes drug classes cut the five-year risk of serious kidney decline by roughly 40%, but only in patients who already...
- AI model predicts which memory-impaired patients will develop dementia within two years
A machine-learning tool trained on data from 828 people with mild cognitive impairment correctly identified who would progress to dementia within two years about 82% of the time. The model drew on...
- Blocking growth hormone receptors in middle-aged mice extended lifespan by under 10%
A new mouse study found that disabling growth hormone receptors at the equivalent of midlife still lengthened lifespan, but only modestly, and the effect was smaller in females. The researchers...
- Why Americans Keep Buying Treatments That Do Not Work
A physician and author who studies medical fads tells MedPage Today that the answer is not stupidity but something more human: nobody wants to die. With social media amplifying unproven claims and...
- Kimchi bacterium doubled nanoplastic excretion in mice in early lab study
Researchers at the World Institute of Kimchi found that a lactic acid bacterium isolated from kimchi bound to nanoplastics under simulated gut conditions and more than doubled the amount excreted...
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